CBD and Gabapentin for Dogs: Safety, Interactions & Side Effects

CBD and Gabapentin for Dogs: Safety, Interactions & Side Effects
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Key Takeaways

  • When CBD and gabapentin are used together, they can make your dog extra sleepy or a bit wobbly, so it’s definitely something to keep an eye on.
  • Talk to your vet before combining them. Getting the right dose and timing isn’t just helpful, it’s super important for your dog’s safety.
  • Gabapentin is a prescription go-to for pain and seizures, while CBD is a more natural, non-intoxicating option to improve calmness, mobility, and overall wellbeing.
  • If your pup seems overly drowsy, starts stumbling, or isn’t eating like usual, it’s time to check in with your vet; those can be signs of a reaction.
  • Bailey’s CBD keeps things dog-friendly with products like calming oils, joint-support chews, soothing balms, and even shampoos—all made to help your dog feel their best, naturally.

Understanding CBD & Gabapentin

CBD is a natural compound from hemp seed that works with your dog’s endocannabinoid system, the part that helps regulate things like mood, stress, and discomfort. It’s become a go-to for many pet parents looking for a gentle, plant-based way to support their dog’s well-being. 

Gabapentin, meanwhile, is a human medication that vets commonly use for dogs, too. It’s especially helpful for nerve pain, anxiety, or stiffness and works by calming the nervous system.

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Safety Profiles

CBD Safety

CBD has a good safety record when used properly. Some dogs might get a bit drowsy or have loose stools, but nothing too dramatic. The key is picking a high-quality product with clear dosing. And if your dog is already on medications like gabapentin, definitely check with your vet first, just to make sure everything plays nicely together.

Gabapentin Safety

Gabapentin is pretty safe when your vet handles the dosing. You might notice your pup acting a little sleepy or wobbly, and sometimes it can upset their tummy. Just be cautious with the liquid human version because it can contain xylitol, which is dangerous for dogs.

Gabapentin is generally safe for dogs when prescribed by a vet, though side effects like drowsiness or tummy upset can happen. Always double-check ingredients.

Potential Interactions Between CBD & Gabapentin

CBD and gabapentin both have calming effects, which is great, unless they work a little too well together. 

When combined, they can make your pup extra sleepy or a bit wobbly. CBD may also affect how the liver processes medications, which might cause gabapentin to be in the system longer than intended. 

That’s why it’s best not to mix the two without your vet’s input. Some vets do use them together, but only with careful dosing and close observation.

Side Effects to Monitor

If your pup is on gabapentin, with or without CBD, keep an eye out for signs like extreme sleepiness, stumbling, tummy trouble, or acting confused. If you’re introducing CBD into the mix, go slow and always loop your vet in; better safe than sorry!

Guidelines for Responsible Use

Here are some key things to keep in mind when considering gabapentin and CBD for your dog:

  • Veterinary Consultation: Talk to your vet before starting your dog on gabapentin, CBD, or both. It’s not something you want to DIY—your vet knows best.
  • Dosage Control: Stick to the dosing plan your vet gives you. Don’t tweak it on your own, even if your dog seems fine (or not).
  • Product Selection: Go with high-quality CBD made just for pets. Look for organic options that are third-party tested so you know exactly what you’re getting.
  • Monitoring: Keep an eye out for signs like extra sleepiness, wobbly walking, or tummy troubles. If anything seems off, check in with your vet.
  • Avoid Abrupt Changes: Never stop gabapentin cold turkey. Always taper off slowly, and only with your vet’s guidance.
  • Avoid Human Formulations: Human gabapentin liquid can contain xylitol, which is toxic to dogs. Stick to pet-safe versions only.

Making the Safest Choice for Your Dog

When it comes to helping your dog feel their best, there’s no one-size-fits-all answer. Every dog is different; what works wonders for one might not work at all for another. That’s why it’s so important to team up with your vet and build a plan that fits your dog’s unique needs. 

If that includes CBD, gabapentin, a mix of both, or something totally different, the goal is always the same: to keep your pup comfortable, happy, and thriving. And as your dog’s needs change, don’t be afraid to tweak the plan. Staying flexible and keeping safety first is the smartest way to care for your furry friend.

Bailey’s CBD: Your Partner in Supporting Your Dog’s Comfort Naturally

Keeping your dog comfortable doesn’t have to be a guessing game. Bailey’s CBD has spent years perfecting natural solutions that actually work, and our hemp-derived CBD products are here to help your dog feel their best every day.

Our CBD is sourced from a single reliable USDA organic farm in Colorado. To keep it pure and powerful, we rely on a unique subcritical CO₂ extraction method done by the only U.S. lab that offers it. That means no heat, no solvents—just clean, effective CBD.

Our CBD Oil for Dogs is crafted for everyday relief. 

  • Our CBD Oil for Dogs has no weird fillers or artificial stuff. Just simple yet powerful ingredients like fractionated coconut oil to help your dog absorb the CBD easily and naturally. It’s also easy to measure and give
  • Our Hip & Joint CBD Soft Chews are packed with joint-loving ingredients (e.g.,  CBD-rich hemp, MSM, glucosamine, and green lipped mussel) and taste like a treat. 
  • For skin or paws that need hydration and protection from surfaces like icy sidewalks or hot pavement, CBD Paw & Nose Balm brings quick relief. 
  • The CBD Pet Shampoo is perfect for keeping your dog’s coat shiny and healthy.

Bailey’s is fully licensed by the Department of Health, which means we play by the strictest rules in the industry. Every batch is third-party tested to make sure it's safe, clean, and exactly what your dog needs.

Everything’s made in the USA with natural, vet-approved ingredients. No grains, no GMOs, no soy—just safe, effective care you can feel good about.

Frequently Asked Questions (FAQ)

Can CBD replace gabapentin for my dog's pain management?

Sometimes! For mild to moderate pain, CBD might do the trick. But it really depends on what’s causing the pain. Gabapentin is great for nerve pain, while CBD may help more with inflammation. Don’t switch things up without checking with your vet; they’ll help you figure out the best plan.

How long should I wait between giving my dog CBD and gabapentin?

A good rule of thumb is to space them 2–3 hours apart. That way, you avoid doubling up on drowsiness. Your vet might suggest a different schedule based on your dog’s needs, so keep them in the loop.

Will CBD show up on my dog's bloodwork at the vet?

Not directly. Vets don’t test for CBD, but it can affect liver values in some dogs. Always tell your vet if your dog’s taking CBD because it helps them interpret lab results accurately and adjust care if needed.

Are there certain dog breeds more sensitive to CBD or gabapentin?

Yes! Herding breeds like Collies and Aussies can be extra sensitive, especially if they have the MDR1 gene. Tiny pups, seniors, or dogs with liver/kidney issues also need extra care. Your vet will help fine-tune the dose.

How do I administer Bailey’s CBD products to my dog?

Easy! You can drop our Bailey’s CBD oil right in their mouth or mix it with food. Chews are a tasty treat option, and balms or shampoos are great to keep skin and coat healthy. Just follow the label and check with your vet if you're using other meds.


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

These products have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease.

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